Esa‐Pekka Kumpula

The paper determines the in situ structure of human Cx43 gap junction plaques using cryogenic electron tomography, revealing the role of the C-terminal domain in plaque assembly.

This study determines the structural basis of Cx45 gating and Ca2+ regulation using cryo-EM, revealing a dual steric-electrostatic mechanism.

This study visualizes the activation of semi-conservative dsRNA transcription in cystovirus Φ6 by observing capsid restructuring and transcription complex assembly using cryogenic electron microscopy.

This study investigates how design parameters affect mRNA-DNA origami folding and translation efficiency, showing the importance of ribosome-binding sequences and demonstrating their encapsulation in virus capsids for enhanced delivery.