BiochemistryNature Chemical BiologyPeer-reviewed
A druggable redox switch on SHP1 controls macrophage inflammation
Mei Ying Ng, Meredith Nicole Nix, Guangyan Du…·Edward T. Chouchani
This paper identifies a druggable redox switch on SHP1 that controls macrophage inflammation by developing a covalent agonist targeting a specific cysteine residue.