Xinge Yu

This paper uses a zebrafish model to identify genetic modifiers of thrombosis, finding a novel mutation in prothrombin and additional modifiers like factor X and plasminogen.

This paper develops an ingestible, battery-free robotic interface for chronic gut electrostimulation, showing it can modulate ghrelin levels and has potential for treating gastrointestinal conditions.

This study conducts a multi-ancestry GWAS for venous thromboembolism, identifies novel loci, and validates their function in zebrafish.

This study shows that disrupting the kringle 1 domain of prothrombin in zebrafish causes late-onset mortality due to impaired clot formation, revealing its role in thrombin biosynthesis and activation.