Author

Jiewei Wu

Pfizer (United States)ORCID 0000-0003-0555-6086Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adele XuiD· 1 shared Alicia SolórzanoiD· 1 shared Andrew M. WatkinsiD· 1 shared Bojan Tunguz· 1 shared Christian A. ChoeiD· 1 shared Craig H. KerriD· 1 shared Daphna RothschildiD· 1 shared Do Soon KimiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Adele XuORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMar 22, 2022

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang…·Rhiju Das

This study develops PERSIST-seq and In-line-seq to optimize mRNA stability and translation, finding that in-cell stability is more critical than ribosome load for protein output.

400 citationstop 1%

humanmultiome

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