Author

Douglas R. Lowy

National Institutes of HealthORCID 0000-0003-0635-219XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2

Frequent Co-Authors

Brajendra K. TripathiiD· 2 shared Lulu YuiD· 2 shared Maggie C. CamiD· 2 shared Vladimır MajerčiakiD· 2 shared Zhi‐Ming ZhengiD· 2 shared Alexei V. LobanoviD· 1 shared Antonis E. KoromilasiD· 1 shared Atsuo T. SasakiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Brajendra K. TripathiORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 10, 2025

eIF2B Selectively Anchors and Activates Mutant KRAS

Hyungdong Kim, Shiqi Diao, Kwang‐Jin Cho…·Antonis E. Koromilas

This paper shows eIF2B activates mutant KRAS by forming a complex with SOS at the plasma membrane and regulating glycosphingolipid biosynthesis.

DOI 10.1101/2025.11.10.686860

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 14, 2025

SRSF3 is oncogenic in breast but tumor-suppressive in liver by differential regulation of gene expression

Lulu Yu, Masahiko Ajiro, Alexei V. Lobanov…·Zhi‐Ming Zheng

This study shows SRSF3 is oncogenic in breast cancer and tumor-suppressive in liver cancer through context-dependent gene regulation.

1 citation

mouseexperimental assay

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Cancer BiologyeLifePeer-reviewedNov 28, 2024

The lnc-FANCI-2 intrinsically restricts RAS signaling in HPV16-infected cervical cancer

Haibin Liu, Lulu Yu, Vladimır Majerčiak…·Zhi‐Ming Zheng

This study identifies lnc-FANCI-2 as a regulator of RAS signaling in HPV16-infected cervical cancer, showing its role in lesion progression and patient survival.

3 citations

humanproteomics

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BioinformaticsJournal of Biotechnology and BiomedicinePeer-reviewedJan 1, 2023

cProSite: A web based interactive platform for online proteomics, phosphoproteomics, and genomics data analysis

Dunrui Wang, Xiaolan Qian, Yi‐Chieh Nancy Du…·Douglas R. Lowy

cProSite provides an interactive platform for analyzing proteomics, phosphoproteomics, and genomics data from CPTAC to compare tumor and normal tissue molecular alterations.

58 citationstop 3%

humanproteomics

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