Author

Antonis E. Koromilas

Jewish General HospitalORCID 0000-0003-1972-0799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

Hyungdong KimiD· 3 shared Jia Yi ZouiD· 3 shared Shiqi DiaoiD· 3 shared Maria HatzoglouiD· 2 shared Nahum SonenbergiD· 2 shared Nour Ghaddar· 2 shared Peter WalteriD· 2 shared Aldo Hernández-CorchadoiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

Hyungdong KimORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivPreprintJan 16, 2026

A Multiomic Analysis of Cachectic Mice Reveals Cancer Driven Suppression of Muscle Stem Cell Differentiation

Darren M. Blackburn, Aldo Hernández-Corchado, Korin Sahinyan…·Vahab D. Soleimani

This study identifies cancer-driven suppression of muscle stem cell differentiation in cachectic mice through GDF15 and MMP9, revealing a new mechanism of muscle wasting.

DOI 10.64898/2026.01.12.699072

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 10, 2025

eIF2B Selectively Anchors and Activates Mutant KRAS

Hyungdong Kim, Shiqi Diao, Kwang‐Jin Cho…·Antonis E. Koromilas

This paper shows eIF2B activates mutant KRAS by forming a complex with SOS at the plasma membrane and regulating glycosphingolipid biosynthesis.

DOI 10.1101/2025.11.10.686860

humanmouse

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Cancer BiologyCommunications BiologyPeer-reviewedAug 25, 2025

A feedforward loop between STAT1 and YAP1 stimulates lipid biosynthesis, accelerates tumor growth, and promotes chemotherapy resistance in mutant KRAS colorectal cancer.

Shuo Wang, Shiqi Diao, Hyungdong Kim…·Antonis E. Koromilas

8 citations

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintFeb 10, 2025

Lineage plasticity of the integrated stress response is a hallmark of cancer evolution.

Shiqi Diao, Jia Yi Zou, Shuo Wang…·Antonis E. Koromilas

This study shows that activation of the integrated stress response (ISR) drives tumor evolution and therapy resistance by promoting dedifferentiation and stemness in lung adenocarcinoma.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky