Author

Felicia Tai

University Health NetworkORCID 0000-0003-0652-6946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. Murison· 1 shared Alexandra N. Fedor· 1 shared Benjamin Haibe‐KainsiD· 1 shared C.H. ArrowsmithiD· 1 shared Daniel DeCarvalho· 1 shared David W. CesconiD· 1 shared Geneviève DebloisiD· 1 shared Giacomo GrilloiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Alexander J. Murison

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1 paper

Recent·Most cited

Metabolic adaptations underlie epigenetic vulnerabilities in chemoresistant breast cancer.

Geneviève Deblois, Seyed Ali Madani Tonekaboni, Yunchi Ingrid Kao, Felicia Tai, Xiaojing Liu, Ilias Ettayebi, Paul Guilhamon, Alexandra N. Fedor, Giacomo Grillo, Alexander J. Murison, Wail Ba-Alawi, David W. Cescon, C.H. Arrowsmith, Daniel DeCarvalho, Morag Park, , Mathieu Lupien

This study identifies metabolic adaptations in taxane-resistant triple-negative breast cancer cells that lead to epigenetic vulnerabilities, specifically through altered methionine metabolism and H3K27me3 redistribution.

bioRxiv · Mar 28, 2018 · PreprintGenomics