Molecular BiologyFrontiers in Cellular and Infection MicrobiologyPeer-reviewed
Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA
Samantha Barichievy, Jerolen Naidoo, Mikaël Boullé…·Musa M. Mhlanga
This study shows HIV-1 evades apoptosis in macrophages by manipulating the MAP2K1/ERK2 pathway to dysregulate lincRNA-p21, and suggests MAP2K1/ERK2 inhibitors as a therapeutic strategy.
40 citations