Author

Anna K. Coussens

University of Cape TownORCID 0000-0002-7086-2621Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adrian R. MartineauiD· 1 shared Alex SigaliD· 1 shared Christopher K. BarlowiD· 1 shared Evelyn Yu‐Wen HuangiD· 1 shared Frank BrombacheriD· 1 shared Ivanhoe K. H. LeungiD· 1 shared Janine ScholefieldiD· 1 shared Jemila C. KesteriD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

Adrian R. MartineauORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 3, 2026

A mixer tap mechanism in Mycobacterium tuberculosis regulates a critical metabolic node in response to nutrient availability

Evelyn Yu‐Wen Huang, Katherine J. Jeppe, Jingsong Zhou…·Ivanhoe K. H. Leung

The paper identifies a regulatory mechanism in Mycobacterium tuberculosis that controls metabolic flux through coordinated enzyme abundance and metabolite effects, likened to a mixer tap.

DOI 10.64898/2026.04.29.721766

metabolomicsexperimental assay

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MicrobiologybioRxivPreprintJun 11, 2025

Digital PCR detection of Mycobacterium tuberculosis and HIV-1 co-localization in spinal tuberculosis biopsies

Robyn Waters, Adrian R. Martineau, Maritz Laubscher…·Anna K. Coussens

The paper uses ddPCR to detect and quantify Mtb and HIV-1 in spinal tuberculosis biopsies, finding reciprocal relationships between pathogen abundance and immune microenvironment factors.

DOI 10.1101/2025.06.11.659223

humanDNA methylation

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Molecular BiologyFrontiers in Cellular and Infection MicrobiologyPeer-reviewedAug 3, 2018

Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA

Samantha Barichievy, Jerolen Naidoo, Mikaël Boullé…·Musa M. Mhlanga

This study shows HIV-1 evades apoptosis in macrophages by manipulating the MAP2K1/ERK2 pathway to dysregulate lincRNA-p21, and suggests MAP2K1/ERK2 inhibitors as a therapeutic strategy.

40 citations

humanDNA methylation

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