Michael J Parisi

The paper introduces SynLight, a dicistronic construct that simultaneously labels presynaptic active zones and neuronal membranes in Drosophila, demonstrating its effectiveness in visualizing and quantifying synapses.

The paper introduces a conditional marker, dlg1[4K], to label endogenous excitatory postsynapses in Drosophila and reveals distinct subsynaptic organization rules across neuron classes.

The paper shows that sequential axon arrival and physical occupancy determine the integration of visual projection neurons onto the dendrites of the giant fiber in Drosophila.

This study shows γ-secretase promotes postsynaptic maturation by cleaving the Wnt receptor Fz2 in Drosophila, linking synaptic development to neurodegenerative disease mechanisms.

The paper identifies the PAF1 complex as a mediator of expanded GGGGCC repeat transcription in C9orf72-associated FTD, showing its role in RNA toxicity and disease progression.