Author

Ryan P. Staupe

University of PennsylvaniaORCID 0000-0003-0793-524XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Allison R. GreenplateiD· 1 shared Amy E. BaxteriD· 1 shared David B. WeineriD· 1 shared Divij MathewiD· 1 shared E. John WherryiD· 1 shared Jennifer E. WuiD· 1 shared Josephine Ruth GilesiD· 1 shared Kito NzinghaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Allison R. GreenplateORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintMay 18, 2026

PD-1 blockade drug holiday improves exhausted progenitor CD8 T cell (Tpex) reinvigoration by avoiding Tpex adaptive resistance

Shin Foong Ngiow, Ryan P. O’Connell, Sasikanth Manne…·E. John Wherry

The paper shows that a drug holiday during PD-1 blockade improves reinvigoration of exhausted T cells by restoring progenitor cell function and reducing adaptive resistance.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky