Yasmin L. Hurd

This study shows ketamine reduces heroin-seeking in rats by modulating endogenous opioid and glutamatergic systems, suggesting its potential as an OUD treatment.

The paper identifies synaptic bioenergetic remodeling in the mPFC after heroin abstinence, but not cocaine, and links it to relapse vulnerability.

The paper examines transcriptomic changes in D1 and D2 medium spiny neurons of the nucleus accumbens after cocaine and morphine exposure, revealing shared and divergent regulatory patterns.

This study identifies transcriptional changes in the brain reward circuit across heroin exposure and seeking behaviors in mice, revealing molecular mechanisms and potential therapeutic targets for opioid use disorder.

This study shows that THC inhibits Hedgehog signaling in embryos, causing developmental defects, and acts as a conditional teratogen when combined with genetic risk factors.