Patricia P. Chan

The paper presents the first telomere-to-telomere diploid reference genome of the human embryonic stem cell line H9, revealing genomic features and ancestry.

RNAcentral integrates literature and gene-level data to enhance non-coding RNA sequence analysis and functional understanding.

This study examines tRNA and tRNA-derived RNA (tDR) expression and modification across 19 mouse tissues, revealing tissue-specific patterns and regulatory mechanisms.

R2DT is a software platform for visualizing RNA secondary structures with enhanced features like SNP display and template-free visualization.

The paper identifies the roles of TRMT1 and TRMT1L in tRNA modifications, showing their impact on tRNA stability and function, and links TRMT1 variants to disease.

The paper proposes a standardized ontology for naming tRNA-derived RNAs based on molecular origin to improve inter-study comparisons.

tRAX is a tool for analyzing tRNAs and tRNA-derived small RNAs, demonstrating its effectiveness in characterizing these transcriptomes in mouse tissues.

The paper improves tRNAscan-SE for better detection and classification of tRNA genes across diverse genomes and introduces mitochondrial tRNA detection.

R2DT generates standardised 2D RNA structure diagrams for diverse ncRNA types using a template library, producing a large dataset of visualisations.

The paper analyzes antibiotic resistance gene distribution in E. coli isolates, identifying two distinct resistance gene clusters with functional redundancy and widespread horizontal transfer.