Chuanxin Zhang

This study shows that HSPA2 expression in mouse 2-cell embryos influences the first cell-fate decision by affecting inner cell mass differentiation.

This study compares poly(A) tail dynamics during oocyte-to-embryo transition across four mammalian species, identifying conserved and divergent features of maternal mRNA regulation.

This study identifies the mechanism of first lineage segregation in human embryos through cell polarisation, showing it occurs at the 8-cell stage via F-actin and Par complex polarisation, with PLC activation and GATA3 regulation.