Marta N. Shahbazi

The paper shows that dynein-dependent organelle clustering during oxidative stress enhances gene expression by coordinating organelle positioning.

This paper develops an in vitro model of the human chorion using blastocysts to generate trophoblast organoids and extraembryonic mesoderm cells, enabling study of placental development and pathophysiology.

The paper shows that non-apical mitoses in the mouse gastrulation streak, driven by actomyosin relaxation and accelerated cell cycles, contribute to cell delamination, but not mesoderm identity.

This study identifies the mechanism of first lineage segregation in human embryos through cell polarisation, showing it occurs at the 8-cell stage via F-actin and Par complex polarisation, with PLC activation and GATA3 regulation.