Jack Hearn

The paper investigates how environmental pollutants like PAHs affect insecticide resistance in malaria vectors through multi-generational selection experiments and transcriptomic analysis.

The paper identifies over-expression and copy number variation of cytochrome P450 and UDP-glucuronosyltransferase genes in ML-resistant Psoroptes ovis mites from cattle.

This study identifies a QTL and associated polymorphisms conferring resistance to alpha-cypermethrin in Anopheles funestus using genetic crosses and BSA mapping.

This study uses genomic data to analyze A. lumbricoides transmission patterns and the impact of repeated drug treatment in a longitudinal cohort.

This study identifies a single mutation G454A in CYP9K1 as a driver of pyrethroid resistance in Anopheles funestus, reducing bed net efficacy and highlighting the need for resistance monitoring.

This study identifies the E205D mutation in CYP6P3 as a driver of pyrethroid resistance in Anopheles gambiae, showing its association with resistance and its interaction with kdr mutations.

The paper identifies overexpression and nonsynonymous mutations in UGT genes associated with pyrethroid resistance in Anopheles funestus using GWAS-PoolSeq and transcriptomic analysis.

MagnaExtract is a magnetic bead-based DNA extraction method for detecting antimicrobial resistance genes in river water, showing comparable or better performance than commercial kits and crude methods.

The paper identifies piRNA-producing clusters in Daphnia magna and shows their expression changes with maternal age, affecting germline piRNA profiles and potentially impacting genome stability.

This study identifies a CYP9K1 haplotype associated with pyrethroid resistance in Anopheles funestus using multi-omics analysis and functional validation.

The paper identifies molecular drivers of insecticide resistance in Anopheles coluzzii populations across the Sahel region, highlighting key genes and chromosomal inversions associated with resistance to pyrethroids and other insecticides.

This study shows that caloric restriction in Daphnia magna causes extensive gene expression changes, including a shift in haemoglobin isoform preference, similar to hypoxia responses.

This study examines DNA methylation changes in Daphnia magna under caloric restriction, identifying differentially methylated regions and their functional implications.