Author

Valentina Rosti

Institute of Biomedical Technologies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chiara LanzuoloiD· 4 shared Emanuele Di Patrizio SoldateschiiD· 3 shared Alessio ColantoniiD· 1 shared Andrea CeraseiD· 1 shared Andrea ScaloniiD· 1 shared Annunziata D’EliaiD· 1 shared Baihui WangiD· 1 shared Benjamin SchuleriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersMolecular Biology

Chiara LanzuoloORCID

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Author profile →

4 papers

Recent·Most cited

The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation

Silvia Piscitelli, Emanuela Cascone, Chiara DˈAmbrosio, Giuseppina Divisato, Emilia Giannino, Laura De Lisio, Guido Leoni, Daniel D’Andrea, Danilo Swann Matassa, Chiara Lanzuolo, Valentina Rosti, Maria Chiara Zizolfi, Monica Matuozzo, Emanuele Di Patrizio Soldateschi, Paolo Maiuri, , Silvia Parisi

This study shows that LIN28A mediates RNA-dependent interactions with PRC2 to regulate chromatin dynamics and neuronal differentiation in ESCs.

Cell Death and Differentiation · May 5, 2026Peer-reviewedMolecular Biology

LBR nucleoplasmic domains regulate X-chromosome solubility and nuclear organization

Jonathan Fiorentino, Irene Perotti, Nerea Ruiz Blanes, Valentina Rosti, Ioanna Sigala, Eleni Nikolakaki, Alessio Colantoni, Annunziata D’Elia, Roberto Massari, Ferdinando Scavizzi, Marcello Raspa, Michela Ascolani, Neil E. Humphreys, Thomas Giannakouŕos, Mitchell Guttman, , Andrea Cerase

This study shows that LBR nucleoplasmic domains regulate X-chromosome solubility and nuclear organization during neural differentiation in mouse cells.

bioRxiv · Apr 1, 2026 · PreprintGenetics

The molecular basis of lamin-specific chromatin interactions

Baihui Wang, Rafael Kronenberg‐Tenga, Valentina Rosti, Emanuele Di Patrizio Soldateschi, Qiang Luo, Ugo Maria Iannacchero, Louise Pinet, Matthias Eibauer, Rajaa Boujemaa‐Paterski, Benjamin Schuler, Chiara Lanzuolo, Ohad Medalia

This study identifies the molecular interactions between lamin isoforms and chromatin, revealing their role in chromatin organization and epigenetic regulation.

Nature Structural & Molecular Biology · Aug 1, 2025Peer-reviewedCell Biology

Biochemical properties of chromatin domains define genome compartmentalization

Federica Lucini, Cristiano Petrini, Elisa Salviato, Koustav Pal, Valentina Rosti, Francesca Gorini, Philina Santarelli, Roberto Quadri, Giovanni Lembo, Giulia Graziano, Emanuele Di Patrizio Soldateschi, Ilario Tagliaferri, Eva Pinatel, Endre Sebestyén, Luca Rotta, , Francesco Ferrari

The paper develops 4f-SAMMY-seq to map euchromatin and heterochromatin based on accessibility and solubility, and reconstructs their 3D compartmentalization in one experiment.

Nucleic Acids Research · May 16, 2024Peer-reviewedGenomics