Author

Wan Jun Gan

The University of QueenslandORCID 0000-0003-0917-1300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alpha S. YapiD· 1 shared Edna C. HardemaniD· 1 shared Helen E. AbudiD· 1 shared Ivar NoordstraiD· 1 shared Jakob BeguniD· 1 shared Peter William GunningiD· 1 shared Rabina GiriiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alpha S. YapORCID

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1 paper

Recent·Most cited

Cell BiologyCytoskeletonPeer-reviewedJul 10, 2024

A truncation mutant of adenomatous polyposis coli (APC) impairs apical cell extrusion through elevated epithelial tissue tension

Wan Jun Gan, Rabina Giri, Jakob Begun…·Ivar Noordstra

This study shows that an APC truncation mutant increases epithelial tissue tension via RhoA/ROCK, impairing apical cell extrusion and potentially contributing to disease.

2 citations

humanorganoid / primary culture

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