Jing Yang

Synergistic interactions between Bacteroides intestinalis and Arabinoxylan Mitigates Inflammatory and Metabolic Dysfunction

This study shows that pairing Bacteroides intestinalis with arabinoxylan reduces inflammation and metabolic issues in mice by altering metabolism and gene expression.

Centrosome-assisted assembly of the Balbiani body

This study shows that centrosome components like Sas6, Cenexin, and DZIP1 promote Xvelo assembly into a Bb-like structure in somatic cells.

PTBP1 mediates Sertoli cell actin cytoskeleton organization by regulating alternative splicing of actin regulators

The paper identifies PTBP1's role in regulating alternative splicing of actin regulators to control Sertoli cell actin cytoskeleton dynamics during spermatogenesis.

Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes

This study shows that reducing RREB1 in mice and humans decreases adipogenesis and improves insulin sensitivity, linking RREB1 to type 2 diabetes risk.

Dzip1 is dynamically expressed in the vertebrate germline and regulates the development of Xenopus primordial germ cells.

This study identifies Dzip1 as a novel germ plasm component in Xenopus and zebrafish that interacts with Dazl to regulate primordial germ cell development.

Phase transition of maternal RNAs during vertebrate oocyte-to-embryo transition

The paper identifies maternal RNA phase transitions during Xenopus oocyte-to-embryo transition, showing distinct soluble and insoluble states and their conservation in zebrafish.

A genome-wide CRISPR screen identifies regulators of beta cell function involved in type 2 diabetes risk

A genome-wide CRISPR screen in human pancreatic beta cells identifies 580 genes influencing insulin content, supporting 20 candidate type 2 diabetes effector transcripts.

PTBP1/HNRNP I controls intestinal epithelial cell regeneration by maintaining stem cell survival and stemness

This study identifies PTBP1 as essential for intestinal stem cell survival and stemness by regulating gene expression through post-transcriptional mechanisms.

Chromatin accessibility and histone acetylation in the regulation of competence in early development

The paper investigates how chromatin accessibility and histone acetylation regulate the loss of competence to inductive signals during early development in Xenopus laevis.