Joseph John Zeppa

This study analyzes the immune response to Bexsero vaccine in mice, showing robust humoral and cellular responses but inconsistent protection against Neisseria gonorrhoeae.

The paper shows that CD4 T cells and innate CD8+ lymphocytes are essential for IV BCG-induced protection against tuberculosis in macaques.

This study selects TbpB variants using phylogenetic analysis to create a bivalent vaccine formulation that elicits broad cross-reactive antibodies and shows efficacy against diverse gonococcal strains.

This study evaluates adjuvant effects on vaccine-induced immunity against Neisseria species, showing adjuvant-dependent protection and no correlation between humoral response and protection.