Author

Jessica Lam

University of TorontoORCID 0009-0009-4272-7543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Scott D. Gray‐OweniD· 3 shared Dixon NgiD· 2 shared Elissa G. Currie· 2 shared Epshita A. Islam· 2 shared Jamie E. Fegan· 2 shared Joseph John ZeppaiD· 2 shared Trevor F. MoraesiD· 2 shared Anthony Bernard SchryversiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

Scott D. Gray‐OwenORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 28, 2025

Network-based population analysis of 31,595 gonococcal genomes reveals phase variability, genetic diversity and mobile element dynamics drive antimicrobial resistance and phenotypic diversity

Duncan Carruthers‐Lay, Jessica Lam, Emil Jurga…·John Parkinson

The paper analyzes 31,595 gonococcal genomes to identify genetic diversity, phase variability, and mobile elements linked to antimicrobial resistance and phenotypic traits.

DOI 10.1101/2025.02.28.640638

humanwhole-genome sequencing

𝕏 PostBluesky

Microbiologynpj VaccinesPeer-reviewedJan 15, 2025

Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae

Jamie E. Fegan, Epshita A. Islam, David M. Curran…·Scott D. Gray‐Owen

This study selects TbpB variants using phylogenetic analysis to create a bivalent vaccine formulation that elicits broad cross-reactive antibodies and shows efficacy against diverse gonococcal strains.

11 citationstop 4%

humancomparative / phylogenetic analysis

𝕏 PostBluesky

ImmunologyVaccinePeer-reviewedSep 12, 2024

Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria

Epshita A. Islam, Jamie E. Fegan, Joseph John Zeppa…·Scott D. Gray‐Owen

This study evaluates adjuvant effects on vaccine-induced immunity against Neisseria species, showing adjuvant-dependent protection and no correlation between humoral response and protection.

10 citations

mouseproteomics

𝕏 PostBluesky