Author

Triantafyllia R. Karakousi

New York UniversityORCID 0000-0002-1950-7341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Amanda W. LundiD· 3 shared Alec C. KimmelmaniD· 1 shared Alec P. BreazealeiD· 1 shared Ananda W. GoldrathiD· 1 shared Anthony SantellaiD· 1 shared Anthony Y. TaoiD· 1 shared Ashley SchreieriD· 1 shared Ata S. MoshiriiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Amanda W. LundORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A tumor metabolism-angiogenesis-immune axis governs immunotherapy responses

Inna S. Serganova, Giorgia Colombo, Francesco Ballesio, Jee Hye Kang, Triantafyllia R. Karakousi, Tullio Esposito, Ellen Ackerstaff, Anthony Santella, Ronald G. Blasberg, Nagavarakishore Pillarsetty, Ashley Schreier, Eleni Andreopoulou, Sandra Demaria, Amanda W. Lund, Pier Federico Gherardini, Roberta Zappasodi

This study shows that reducing tumor glycolysis improves immunotherapy responses by normalizing the tumor microenvironment and enhancing immune cell activity.

bioRxiv · Feb 24, 2026 · PreprintImmunology

IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma

Triantafyllia R. Karakousi, Vanessa Cristaldi, Maria Luiza Lopes de Oliveira, Ines Delclaux, Naomi R. Besson, Luiz Henrique Geraldo, Tania J González-Robles, Devyon R. McDonnough, Daniel Martinez-Krams, Gabrielle Silva, Alec P. Breazeale, Joel Encarnación-Rosado, Joanna Poźniak, Shi Qiu, Irineu Illa Bochaca, , Amanda W. Lund

This study shows that IFNγ suppresses lymphatic vessel growth and metastasis by altering metabolism and immune function in melanoma.

Cancer Cell · Jan 22, 2026Peer-reviewedCancer Biology

Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells

Derek J. Bangs, Brian D. Hondowicz, Kathleen Abadie, Remi Savard, Madeleine A. Weiss, Triantafyllia R. Karakousi, Peter J. Skene, Amanda W. Lund, Ananda W. Goldrath, Maximilian Heeg, Marion Pepper

This study identifies two distinct CD4+ T cell populations in inflamed lungs, showing that TCF1+ progenitor cells in tertiary lymphoid structures drive Th2 responses in allergic disease.

bioRxiv · Oct 3, 2025 · PreprintImmunology

Targeting DNA Polymerase Epsilon Leads to Tumor Clearance and Activation of an NF-κB mediated inflammatory response in Triple Negative Breast Cancer

Elizabeth F. Sher, Kenji Mark Fujihara, Anthony Y. Tao, Diana Erenburg, Vladislav O. Sviderskiy, Hannan Mir, Triantafyllia R. Karakousi, Cynthia A. Loomis, Jiehui Deng, Kwok‐Kin Wong, Richard Possemato

This study shows that inhibiting DNA polymerase epsilon in TNBC triggers an NF-κB-driven inflammatory response and tumor clearance in mice.

bioRxiv · Sep 18, 2025 · PreprintCancer Biology