Author

Kate M. MacDonald

Stanford UniversityORCID 0000-0003-1239-0459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Shane M. HardingiD· 2 shared Anthony V. Columbus· 1 shared Christopher J. BakkenistiD· 1 shared Daniel IvanoviD· 1 shared Frank P. VendettiiD· 1 shared Jan Hendrik BeumeriD· 1 shared Joseph El-Ghoubaira· 1 shared Joshua J. DeppasiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Shane M. HardingORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 20, 2025

MicroNucML: A machine learning approach for micronuclei segmentation and the refinement of nuclei-micronuclei relationships

Yu–Kai Wang, Nadejda B. Boev, Ulises Omar García‐Lepe…·Sushant Kumar

This paper introduces a machine learning tool for micronuclei segmentation and refines nuclei-micronuclei relationships using a two-phase labeling approach and a Mask-RCNN model.

DOI 10.1101/2025.09.20.677550

imagingmachine learning (classical)

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Cancer BiologybioRxivPreprintApr 4, 2024

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

Pinakin Pandya, Frank P. Vendetti, Joseph El-Ghoubaira…·Christopher J. Bakkenist

The paper shows that dU-rich cytoplasmic DNA inhibits STING-dependent immune responses and enhances anti-PD-L1 therapy efficacy in tumors.

2 citations

mouseDNA methylation

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