Kechun Tang

Catestatin improves heart metabolic flexibility by promoting mitochondrial structure and function

This study shows that Catestatin improves heart metabolic flexibility by enhancing mitochondrial structure and function through binding to ATP synthase.

Catestatin ameliorates tauopathy and amyloidogenesis via adrenergic inhibition

This study shows that Catestatin reduces Tau pathology and amyloid plaque formation by inhibiting adrenergic signaling in mouse models of neurodegenerative diseases.

Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling

This study investigates the roles of CgA and its derived peptides, CST and PST, in pancreatic islet function and glucose homeostasis using knockout mice, revealing their opposing effects on insulin resistance and metabolic processes.

Catestatin suppresses melanoma progression and drug resistance through multitargeted modulation of signaling pathways

This study shows that CST suppresses melanoma progression and drug resistance by modulating multiple signaling pathways.

Chromogranin A Deficiency Attenuates Tauopathy by Altering Epinephrine Alpha-Adrenergic Receptor Signaling

This study shows that CgA deficiency reduces tau pathology and improves cognitive function in tauopathy models by modulating epinephrine-alpha-adrenergic receptor signaling.