Author

Mandy Koopman

University Medical Center GroningenORCID 0000-0003-1429-2078Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ellen A. A. NolleniD· 2 shared Leen JansseniD· 2 shared Alejandro Mata‐CabanaiD· 1 shared Anita PrasiD· 1 shared Bert HoubeniD· 1 shared Christian GallreiniD· 1 shared Esther Stroo· 1 shared Francesco A. AprileiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Ellen A. A. NollenORCID

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2 papers

Recent·Most cited

Molecular BiologyThe EMBO JournalPeer-reviewedOct 7, 2021

The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation

Anita Pras, Bert Houben, Francesco A. Aprile…·Ellen A. A. Nollen

The paper identifies MOAG-4/SERF as modifiers of amyloid formation through charge complementation, showing that charge interactions drive protein aggregation and toxicity.

25 citations

C. elegansprotein structure

𝕏 PostBluesky

GeneticsbioRxivPreprintMar 19, 2021

Optogenetic manipulation of individual or whole population Caenorhabditis elegans worms with an under hundred-dollar tool: the OptoArm

Mandy Koopman, Leen Janssen, Ellen A. A. Nollen

The paper introduces an affordable optogenetic device called OptoArm for manipulating C. elegans worms, showing that cholinergic neurons decline with age while GABAergic neurons and muscle cells remain resilient.

1 citation

C. elegansexperimental assay

𝕏 PostBluesky