The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
Anita Pras, Bert Houben, Francesco A. Aprile, Renée I. Seinstra, Rodrigo U. Gallardo, Leen Janssen, Wytse Hogewerf, Christian Gallrein, Matthias De Vleeschouwer, Alejandro Mata‐Cabana, Mandy Koopman, Esther Stroo, Minke de Vries, Samantha Louise Edwards, Janine Kirstein, , Ellen A. A. Nollen
The paper identifies MOAG-4/SERF as modifiers of amyloid formation through charge complementation, showing that charge interactions drive protein aggregation and toxicity.
The EMBO Journal · Oct 7, 2021Peer-reviewedMolecular Biology