Anne Bremer

Multivalent Tau-Fyn interactions cooperatively arrest postsynaptic density condensate dynamics

This study investigates how Tau and Fyn interact to regulate postsynaptic density condensate dynamics, showing that their multivalent interactions cooperatively arrest condensate components.

Viscoelasticity and interface properties of multi-component condensates govern protein sequestration and suppression of amyloid formation

This study shows multi-component biomolecular condensates suppress amyloid formation by sequestering proteins, limiting their availability for fibril formation.

Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function

This study compares two models of transcription factor function in yeast, showing that Gcn4 can act through both soluble complexes and condensates, with DNA binding suppressing phase separation.

Biomolecular condensates are characterized by interphase electric potentials

The paper shows that biomolecular condensates generate interphase electric potentials due to ion asymmetry, suggesting they function as mesoscale capacitors.