Author

Aaron B. Taylor

St. Jude Children's Research HospitalORCID 0000-0002-4192-2453Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aseem Z. AnsariiD· 2 shared Tanja MittagiD· 2 shared Walter H. Lang· 2 shared Adithi DandaiD· 1 shared Anang A. ShelatiD· 1 shared Anne BremeriD· 1 shared Ashraf MohammediD· 1 shared Beisi XuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Aseem Z. AnsariORCID

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2 papers

Recent·Most cited

BRD4 recruitment desilences transcription without erasure or depletion of repressive chromatin

Christopher J. Brandon, Sarah Robinson-Thiewes, Mangesh H. Kaulage, Wojciech Rosikiewicz, Matthew J. Cuneo, Joseph Brett, Jindpreet Kandola, Walter H. Lang, Jonathan A. Low, Ashraf Mohammed, Adithi Danda, Sam Rider, M Valentine, Jason Ochoada, Brandon Michael Young, , Aseem Z. Ansari

This study shows that BRD4 recruitment can desilence transcription within repressive chromatin without removing H3K9me3 or HP1, challenging conventional models of chromatin regulation.

bioRxiv · Apr 13, 2026 · PreprintCell Biology

Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function

Anne Bremer, Walter H. Lang, Ryan P. Kempen, Kumari Sweta, Aaron B. Taylor, Madeleine B. Borgia, Aseem Z. Ansari, Tanja Mittag

This study compares two models of transcription factor function in yeast, showing that Gcn4 can act through both soluble complexes and condensates, with DNA binding suppressing phase separation.

Molecular Cell · Jul 1, 2025Peer-reviewedBiophysics