Robert Buschauer

Recognition and deubiquitination of free 40S for translational reset by Otu2

The paper identifies Otu2's role in deubiquitinating eS7 on recycled 40S ribosomal subunits to reset translation, revealing structural mechanisms for this process.

Ribosome collisions in bacteria promote ribosome rescue by triggering mRNA cleavage by SmrB

The paper identifies SmrB as a factor that cleaves mRNAs upstream of stalled ribosomes in bacteria, promoting ribosome rescue through ribosome collisions.

Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.

The paper presents cryo-EM structures of hibernating yeast and human ribosomes, showing Lso2/CCDC124 binds in a non-rotated state, enabling rapid translation reactivation.

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

This study reveals how SARS-CoV-2 Nsp1 protein inhibits host translation and immune responses by binding ribosomes and blocking mRNA entry.

The Ccr4-Not complex monitors the translating ribosome for codon optimality

The paper shows the Ccr4-Not complex interacts with the ribosome's E-site when codon optimality is low, linking translation efficiency to mRNA stability.