Author

Lucas Schoenfeldt

ETH ZurichORCID 0000-0003-1487-0747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alejandro OcampoiD· 3 shared Alberto ParrasiD· 2 shared Amin HaghaniiD· 2 shared Calida Mrabti· 2 shared Kevin PéreziD· 2 shared Robert T. BrookeiD· 2 shared Sara PicóiD· 2 shared Steve HorvathiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersPharmacology & Toxicology

Alejandro OcampoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Pharmacology & ToxicologyAging CellPeer-reviewedJan 24, 2025

Comprehensive evaluation of lifespan-extending molecules in C. elegans

Grace B. Phelps, Jonas Morin, Carla Pinto…·Kevin Pérez

This study evaluates 16 lifespan-extending molecules in C. elegans, confirming some effects, identifying synergies, and finding conserved effects in Drosophila.

15 citations

C. elegansexperimental assay

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PhysiologybioRxivPreprintJul 24, 2024

Loss of H3K9 trimethylation leads to premature aging

Alejandro Ocampo, Calida Mrabti, Gabriela Desdín-Micó…·Yohan Bignon

This study shows that loss of H3K9me3 in adult mice leads to premature aging, characterized by reduced lifespan, frailty, and accelerated epigenetic aging.

21 citations

mouseChIP-seq

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Molecular BiologyAging CellPeer-reviewedDec 22, 2023

ERCC1 mice, unlike other premature aging models, display accelerated epigenetic age

Kevin Pérez, Alberto Parras, Sara Picó…·Alejandro Ocampo

The paper compares DNA methylation age in four premature aging mouse models, finding ERCC1 mice show the most significant increase in epigenetic age.

31 citations

mouseDNA methylation

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