Chi‐Lun Chang

This study identifies CHKA's role in alkylating agent resistance through lipid droplet-mediated regulation of RAD51 transcription in T-ALL.

This study identifies OPA1's role in fatty acid release from lipid droplets and links its function to human metabolism.

This paper introduces BOLT, a tool for inducible trapping, controlled release, and visualization of proteins in living cells, demonstrating its use in tracking protein and organelle dynamics.

The paper shows glucose starvation impairs ER-to-Golgi trafficking, reducing surface proteins like E-cadherin and promoting metastasis through AMPK and ULK1 signaling.

This paper introduces FABCON, a tool for detecting lipid droplet-organelle contact sites in living cells, showing their dynamic behavior under different metabolic conditions.

The paper shows that astrocytes detoxify fatty acids from hyperactive neurons through mitochondrial oxidation, protecting neurons from toxicity.

This study shows EB1 binding acts as a diffusion trap to regulate STIM1 localization and Ca2+ signaling by delaying its translocation to ER-PM junctions.