Author

Bingrong Xu

Huazhong Agricultural UniversityORCID 0000-0003-1568-3855Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Changzhi Zhao· 2 shared Dagang Tao· 2 shared Jinxue RuaniD· 2 shared Liangliang Fu· 2 shared Shuhong ZhaoiD· 2 shared Xinyun LiiD· 2 shared Di Wu· 1 shared Hailong LiuiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersSynthetic Biology

Changzhi Zhao

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 24, 2026

Catalytic rewiring of RuvC-II catalytic site activates trans-cleavage in Fanzor2

Bingrong Xu, Xiaoqiang Huang, Xiaosong Han…·Shuhong Zhao

This study shows that catalytic rewiring of Fanzor2's RuvC-II site activates trans-cleavage, enabling new diagnostic applications.

DOI 10.64898/2026.06.23.733943

DNA methylationproteomics

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Synthetic BiologybioRxivPreprintSep 27, 2024

Expanding the CRISPR toolbox by engineering Cas12a orthologs of metagenomic discovery

Dagang Tao, Bingrong Xu, Sheng Li…·Shengsong Xie

The paper identifies and characterizes new Cas12a orthologs from metagenomic data, leading to variants with improved PAM recognition and editing efficiency for CRISPR applications.

2 citations

statistical modelprotein structure prediction

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Molecular BiologyACS Synthetic BiologyPeer-reviewedDec 23, 2021

Rapid visual CRISPR assay: a naked-eye colorimetric detection method for nucleic acids based on CRISPR/Cas12a and convolutional neural network

Shengsong Xie, Dagang Tao, Yuhua Fu…·Shuhong Zhao

This paper develops a CRISPR/Cas12a-based colorimetric assay with a convolutional neural network for rapid, naked-eye detection of viral nucleic acids in point-of-care testing.

74 citations

deep learningbenchmarking

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