Shengsong Xie

A Rapid and Highly Sensitive CRISPR Assay Utilizing Cas12a Orthologs for the Detection of Novel Duck Reovirus

This paper develops a CRISPR-based assay using Cas12a orthologs for detecting NDRV S3 gene with high sensitivity and visual detection capability.

RBMX2: A Pivotal Regulator Linking Mycobacterium bovis Infection to Epithelial-Mesenchymal Transition and Lung Cancer Progression

This study identifies RBMX2 as a host factor that enhances M. bovis infection and drives infection-induced epithelial-mesenchymal transition, linking TB to lung cancer progression.

GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding

This study identifies GGCX as a key factor enabling EA H1N1 SIV adaptation to human-type -2,6 sialic acid receptors through HA carboxylation, suggesting it as a potential antiviral target.

Rapid visual CRISPR assay: a naked-eye colorimetric detection method for nucleic acids based on CRISPR/Cas12a and convolutional neural network

This paper develops a CRISPR/Cas12a-based colorimetric assay with a convolutional neural network for rapid, naked-eye detection of viral nucleic acids in point-of-care testing.

CRISPR screening of porcine sgRNA library identified host factors essential for Japanese encephalitis virus replication

The paper uses CRISPR screening in porcine cells to identify host factors essential for Japanese encephalitis virus replication and entry.