Kathrin Braun

This study identifies a conserved signaling module involving LIN-42 and KIN-20 that regulates molting timing in C. elegans, mirroring the mammalian PER-CK1 complex.

The paper develops a linear model to predict chromatin dynamics based on transcription factor binding in C. elegans, identifying key regulators that schedule gene expression rhythms.

The paper identifies GRH-1 as a transcription factor essential for rhythmic molting in C. elegans, showing its role in gene regulation and cuticle formation.

The paper shows that proteolytic processing of Argonaute proteins by DPF-3 regulates small RNA association, maintaining genome integrity and fertility in C. elegans.