Author

Stephen P. Methot

Friedrich Miescher InstituteORCID 0000-0003-2854-2226Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:ATAC-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Dimos GaidatzisiD· 1 shared Giovanna BrancatiiD· 1 shared Helder C. FerreiraiD· 1 shared Helge GroßhansiD· 1 shared Hubertus KohleriD· 1 shared Janie C OlveriD· 1 shared Karim Hussain· 1 shared Kathrin BrauniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Dimos GaidatzisORCID

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2 papers

Recent·Most cited

Systems BiologyMolecular Systems BiologyPeer-reviewedOct 10, 2025

A scheduler for rhythmic gene expression

Dimos Gaidatzis, Maike Graf-Landua, Stephen P. Methot…·Helge Großhans

The paper develops a linear model to predict chromatin dynamics based on transcription factor binding in C. elegans, identifying key regulators that schedule gene expression rhythms.

3 citations

C. elegansscRNA-seq

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Molecular BiologybioRxivPreprintMar 11, 2025

ATRX safeguards cellular identity during C. elegans development

Janie C Olver, Mariya Shtumpf, Karim Hussain…·Helder C. Ferreira

This study shows that XNP-1, the C. elegans homologue of ATRX, maintains cellular identity by preventing ectopic germline gene expression, and its loss leads to developmental defects.

DOI 10.1101/2025.03.11.641662

C. elegansexperimental assay

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