Wojciech Krężel

This study investigates RARB-RD mouse models and finds that both GOF and DN variants compromise striatal structure and function, with transcriptional effects more severe than a null allele.

This study shows that reduced RARβ signaling in HD mouse models accelerates motor and transcriptional abnormalities, suggesting a protective role for RARβ in disease progression.

The paper identifies Greb1l as a genetic determinant of criss-cross heart in mice by showing its role in maintaining precursor cells during heart tube elongation.

The paper identifies cell type-specific epigenetic features in a conserved MEIS1 intronic region associated with insomnia and restless legs syndrome, showing their role in MEIS1 regulation.