Olga Vitek A

The paper introduces mzQC, a standard for representing quality control metrics in mass spectrometry, enabling interoperable and machine-readable QC reporting.

MSstatsResponse improves detection of drug-protein interactions in chemoproteomics by using a semi-parametric statistical model that avoids fixed curve shapes, enhancing accuracy and robustness in low-replicate and low-dose settings.

MSstatsBioNet integrates differential proteomics results with biomolecular networks to enable mechanistic interpretation of biological changes.

This paper optimizes and benchmarks synchro-PASEF for phosphoproteomics, showing improved identification and quantification with retention time summation, and comparable performance to dia-PASEF in modeling phosphosignaling.

MSstats+ improves differential protein analysis in proteomic experiments by incorporating longitudinal quality metrics to reduce false positives from poor-quality measurements.

Cardinal v3 provides a versatile open-source tool for reproducible mass spectrometry imaging analysis, supporting advanced data processing and statistical methods for large-scale experiments.

The paper introduces a statistical framework for detecting differential post-translational modification abundance in proteomics data, showing improved fold change estimation and detection compared to existing methods.