Author
Koch Institute for Integrative Cancer Research At MITORCID 0000-0003-1735-7287Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Colin E Fowler, Natalie A. O’Hearn, Nicole Henning…·Jacqueline A. Lees
This study shows PRMT5 inhibition causes splicing defects and epigenetic changes leading to drug resistance and metastatic progression in lung adenocarcinoma.
Shandon M Amos, Chi-Chao Chen, Yichen Xiang…·Yadira M. Soto‐Feliciano
This study identifies TRIM28 as a critical regulator in acute leukemia, showing its depletion promotes neutrophil differentiation and reduces leukemic potential, with a small-molecule inhibitor developed to target it.
Ziyang Ye, Alireza Khademi, Renée Louane Barbosa…·Yadira M. Soto‐Feliciano
This study develops CHANCLA, a multiomic platform to screen oncohistones, revealing their impact on chromatin and cell fate through functional and structural analyses.