Author

Nur Mehpare Kocatürk

University of DundeeORCID 0000-0002-4452-9913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Gajanan J. SatheiD· 2 shared William FarnabyiD· 2 shared Adam L. PintoiD· 1 shared Adrien RousseauiD· 1 shared Amalie N.L. MikkelseniD· 1 shared Arjan Buist· 1 shared Bente FrølundiD· 1 shared Bill CartoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

Gajanan J. SatheORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of a NanoBRET assay platform to detect intracellular target engagement in living cells for the Glycine Transporter 1 (SLC6A9)

Malene Hall Jensen, Ioannis Panagiotis Avgeris, Nur Mehpare Kocatürk, Amalie N.L. Mikkelsen, Bente Frølund, William Farnaby, Petrine Wellendorph, Jonas Sigurd Mortensen, Francesco Bavo

The paper develops a NanoBRET assay to quantify intracellular GlyT1 target engagement in living cells, distinguishing intracellular from extracellular ligands and resolving structure-activity relationships.

bioRxiv · Oct 6, 2026 · PreprintMolecular Biology

Electrophilic Multi-Kinase Probes Identify Degradation and Aspartate Conjugation of ULK1

Nur Mehpare Kocatürk, Adam L. Pinto, Matylda Anna Izert, Léa P. Wilhelm, Gajanan J. Sathe, Qasim Ashraf, Ian G. Ganley, Adrien Rousseau, William Farnaby

The paper identifies a new mechanism of kinase inhibition through electrophilic modifications, revealing aspartate conjugation of ULK1 by a chloroacetamide warhead.

bioRxiv · May 5, 2026 · PreprintBiochemistry

Targeted degradation of α-synuclein prevents PFF-induced aggregation

Bill Carton, Géraldine Gelders, Gajanan J. Sathe, Nur Mehpare Kocatürk, Sascha Röth, Thomas Macartney, Joke Van Elsen, Louis De Muynck, Arjan Buist, Diederik Moechars, Gopal P. Sapkota

This study demonstrates targeted degradation of α-synuclein using a nanobody-guided system, preventing PFF-induced aggregation in neurons.

bioRxiv · Apr 15, 2025 · PreprintNeuroscience