Joe H. Simmons

This study uses a baboon model of sepsis to analyze cardiomyopathy through multimodal techniques, finding distinct transcriptomic and physiological differences between survivors and non-survivors.

This study finds a female mutation bias in aye-ayes, contrasting the typical male mutation bias in mammals, and identifies potential genetic causes.

This paper develops an engineered extracellular vesicles-based vaccine platform for combined mRNA and protein delivery, showing tumor regression and immune responses in preclinical models.

The paper uses primate genetic data to predict human variant pathogenicity with a deep learning classifier trained on 4.3 million common missense variants.

This study presents whole-genome data from 233 primate species, revealing patterns of genetic diversity, mutation rates, and recurrent missense mutations across primate clades.