Rohinton T. Kamakaka

This study shows that heterochromatin stably silences weak regulatory elements but not housekeeping genes, with Sir1 playing a limiting role in silencing.

The paper identifies POLR3G as a key determinant of Pol III transcriptional identity, showing its role in SNAR-A RNA expression and its association with cancer prognosis.

The paper quantifies the threshold of histone acetylation required to switch silent chromatin to active state in budding yeast.

The paper establishes standardized methods and reference materials for measuring wood-degrading fungi growth to enable reproducible and scalable bioproduction.

The paper analyzes regulatory elements in yeast to understand their interactions and develops methods to estimate their contributions to gene expression.

This study shows that removing tRNA genes from a chromosome does not broadly disrupt chromosome folding but affects local nucleosome positioning and SMC protein binding, as well as centromere and heterochromatin clustering.