Jeremy D. Kratz

This study identifies SPINK1 as a regulator of epigenomic states and stemness in PDAC through its interaction with COL18A1 and endostatin release.

This paper describes two patient-derived organoids from a TP53- and KRAS-mutant ovarian carcinoma, showing differential chemotherapy response and using long-read sequencing to characterize structural variants and methylation differences.

This study uses wide-field optical redox imaging to assess treatment response and heterogeneity in colorectal cancer organoids, showing improved sensitivity and accuracy compared to existing methods.

This paper identifies ICAM-1 as a novel hypoimmune target in human pluripotent stem cells, showing that its knock-out reduces immune cell adhesion and enhances graft survival.