Senem Merve Fred

This paper shows that nitric oxide nitrates TRKB receptors, impairing BDNF signaling and reducing neuronal plasticity through endocytosis and degradation.

This study shows that reduced PTPσ expression improves short-term memory but impairs long-term memory retention in mice, suggesting PTPσ's role in memory retention through TRKB signaling.

The paper identifies CRAC and CARC motifs in RTK transmembrane domains, showing cholesterol interaction with TRKB's CARC motif and its effect on BDNF binding.

This study identifies a direct binding of antidepressants to TRKB receptors, revealing a mechanism linking molecular interactions to antidepressant effects.

This study shows that chondroitinase and antidepressants promote plasticity in the adult visual cortex by enhancing TRKB signaling in parvalbumin neurons through inhibition of PTPσ.