Author

Charlotte G. Mann

ETH ZurichORCID 0000-0003-2005-7752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Joshua D. RabinowitziD· 2 shared Michael Robert MacArthuriD· 2 shared Sarah Jayne MitchelliD· 2 shared Alban LongchampiD· 1 shared Coleen Tara MurphyiD· 1 shared Collin Y. EwaldiD· 1 shared Craig J. Hunter· 1 shared Florent AllagnatiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPhysiology

Joshua D. RabinowitzORCID

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2 papers

Recent·Most cited

Pharmacologic AMPK Activation Extends Lifespan in C. elegans and Improves Aspects of Healthspan in Mice

Özlem Altıntaş, Marie Knufinke, Charlotte G. Mann, P. Kent Langston, Joshua D. Rabinowitz, Coleen Tara Murphy, Collin Y. Ewald, Sarah Jayne Mitchell, Michael Robert MacArthur

This study shows that pharmacologic AMPK activation with MK-8722 extends lifespan in C. elegans and improves metabolic health in aged mice.

bioRxiv · Apr 29, 2026 · PreprintPhysiology

Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation

Charlotte G. Mann, Michael Robert MacArthur, Jing Zhang, Songlin Gong, Jenna E. AbuSalim, Craig J. Hunter, Wenyun Lu, Thomas Agius, Alban Longchamp, Florent Allagnat, Joshua D. Rabinowitz, James R. Mitchell, Katrien De Bock, Sarah Jayne Mitchell

SAAR improves exercise capacity in mice by enhancing fat oxidation and substrate availability through VEGF signaling and CD36-dependent fatty acid transport.

iScience · Nov 20, 2025Peer-reviewedPhysiology