Anne‐Marie Lefrançois‐Martinez

This study shows PKA inhibits TRIM28-chromatin binding in ovarian granulosa cells, disrupting ovarian identity through SUMOylation dysregulation.

This study identifies TRIM28's role in preserving ovarian identity by stabilizing lineage-specific transcription factor hubs rather than through H3K9me3-dependent heterochromatin.

This study shows that inhibiting SUMOylation with TAK-981 in mice reduces adipose tissue weight and adipocyte size, mimicking genetic hypoSUMOylation effects.

The paper shows that mutations in PKAc cause displacement from AKAP signaling islands, leading to distinct pathogenic signaling pathways in Cushing's syndrome.