Françis Poulat

This study shows PKA inhibits TRIM28-chromatin binding in ovarian granulosa cells, disrupting ovarian identity through SUMOylation dysregulation.

This study identifies TRIM28's role in preserving ovarian identity by stabilizing lineage-specific transcription factor hubs rather than through H3K9me3-dependent heterochromatin.

This study identifies time- and sex-specific transposable element expression and epigenetic signatures in mouse fetal gonads, suggesting their role in regulating sex-specific gene expression.

This study shows that DMRT1 is essential for testis determination in rabbits and also critical for female fertility, revealing its conserved role across vertebrates.

This study identifies TRIM28's role in preventing female-to-male sex reversal in the adult mouse ovary by maintaining the ovarian pathway through SUMOylation.