Kathleen Abadie

SpatialTRACE extends anatomical annotations from a few structures to tissue-wide maps using graph and image-based models in spatial transcriptomics and microscopy.

This study uses multi-omic profiling to analyze immune cell dynamics in healthy adults over time, finding age-related transcriptional changes in T cells and impaired memory B cell responses in older adults.

This study identifies two distinct CD4+ T cell populations in inflamed lungs, showing that TCF1+ progenitor cells in tertiary lymphoid structures drive Th2 responses in allergic disease.