Vojtěch Žíla

This study shows Lenacapavir causes HIV-1 capsid damage, exposing genomic DNA in nuclear speckles and altering capsid structure.

This study shows that nuclear pore complexes dilate during cell differentiation and that Nup133 deficiency prevents this dilation, leading to nuclear envelope instability.

This study investigates how HIV-1 capsids pass through nuclear pores, finding that capsids retain their structure and cause NPC scaffold rings to crack.