Vibor Laketa

Connecting adhesion dynamics and trail formation in malaria parasites by imaging the major surface antigens CSP and TRAP

This study uses imaging to show how TRAP and CSP dynamics drive adhesion and trail formation in malaria sporozoites, revealing a link between adhesion and trail formation.

Structural characterization of antibodies for synergistic HCMV neutralization

This study uses cryo-EM to analyze antibodies targeting HCMV glycoproteins, identifying synergistic combinations that enhance neutralization.

K5 polysaccharides inhibit SARS-CoV-2 infection by preventing spike-proteolytic priming

This study shows K5 polysaccharides inhibit SARS-CoV-2 by blocking spike binding to ACE2 and furin cleavage, with K5OSH showing stronger antiviral activity than heparin.

Lenacapavir-induced capsid damage exposes HIV-1 genomes from nuclear speckles.

This study shows Lenacapavir causes HIV-1 capsid damage, exposing genomic DNA in nuclear speckles and altering capsid structure.

Passage of the HIV capsid cracks the nuclear pore

This study investigates how HIV-1 capsids pass through nuclear pores, finding that capsids retain their structure and cause NPC scaffold rings to crack.

Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing

This study identifies Nup153 as a docking point for splicing machinery at the nuclear pore, showing its role in mRNA processing and gene splicing.

Alterations of redox and iron metabolism accompany development of HIV latency.

The paper identifies alterations in redox and iron metabolism associated with HIV-1 latency development and suggests iron metabolism modulators as potential therapeutic tools.