Takako Ikeda

This study identifies maternal progesterone signaling through mPRδ as critical for establishing lifelong oral homeostasis via a hormone-lipid-microbiome axis.

This study shows hexanoic acid improves metabolic health in mice on a high-fat diet by reducing weight gain, fat accumulation, and glucose intolerance.

This study shows that GPR109A protects the liver from inflammation during the ketogenic diet by maintaining intestinal barrier integrity through the gut-liver axis.

This study shows that GPR164 deletion in mice causes intestinal barrier dysfunction, Wnt/β-catenin signaling disruption, and IBD-like symptoms, suggesting GPR164 as a therapeutic target for IBD.